Macromolecular Crystallography Macromolecular Crystallography 
The X-ray Crystallography
and Structural Genomics Group at the Biology and Biotechnology
Research Program (BBRP) at Livermore is funded through NIH grants and subcontracts
to BR. We have a CCD detector
system, a crystallization laboratory with extensive robotics thanks to the NIH
TB Structural Genomics Consortium, molecular biology laboratories and additional support facilities dedicated to crystallographic
computing. We work on molecular biology, expression, purification, and crystallization of
macromolecules in a dedicated, modern laboratory equipped with computer controlled
crystallization robots, stereo-microscopes, temperature controlled rooms and general
molecular biology lab equipment such as CD, DLS, centrifuges, gel
electrophoresis units, FPLC and BioCad Perfusion Chromatography systems and
robotic crystallization instrumentation. Our old
but trusty ADSC multiwire area detector system has
been retired and serves as a photon detector in a Compton scattering experiment.
Our ADSC Quantum 4 CCD detector system incorporates
OSMIC confocal mirror design
and improved cryo-cooling equipment. We
are participating research team members at the ALS MAD beamline 5.0.2 and work frequently at SSRL beamline 1-5.