Recent PDB releases or updates: week of 17 May 2000

• 1dd0.pdb. oxidoreductase 05-nov-99 1dd0 (theoretical model)
  Title: molecular model of prostaglandin g2 bound to the cyclooxygenase active site of cox-2
  Author: j. r. kiefer, j. l. pawlitz, k. t. moreland, r. a. stegeman, j. k. gierse, a. m. stevens, d. c. goodwin, s. w. rowlinson, l. j. marnett, w. c. stallings, r. g. kurumbail
  Keywords: cyclooxygenase, prostaglandin, arachidonate, endoperoxide, oxidoreductase
  
• 1ewp.pdb. hydrolase 26-apr-00 1ewp
  Title: cruzain bound to mor-leu-hpq
  Author: s. a. gillmor
  Keywords: drug design, covalent inhibitor, cruzipain
  
• 1duq.pdb. ribonucleic acid 18-jan-00 1duq Na
  Title: crystal structure of the rev binding element of hiv-1
  Author: l. -w. hung, e. l. holbrook, s. r. holbrook
  Keywords: hiv-1, rev binding domain
  
• 1dva.pdb. hydrolase/hydrolase inhibitor 20-jan-00 1dva Ca As
  Title: crystal structure of the complex between the peptide exosite inhibitor e-76 and coagulation factor viia
  Author: c. eigenbrot, m. h. ultsch
  
  
• 1d4q.pdb. membrane protein 05-oct-99 1d4q (NMR, 20 structures)
  Title: nmr structure of the ligand binding domain of the common beta-chain in the gm-csf, il-3 and il-5 receptors
  Author: t. d. mulhern, r. j. d'andrea, c. gaunt, l. vandeleur, m. a. vadas, a. f. lopez, g. w. booker, c. j. bagley
  Keywords: cytokine receptor, fn3 domain
  
• 1dn2.pdb. immune system 15-dec-99 1dn2
  Title: fc fragment of human igg1 in complex with an engineered 13 residue peptide dcawhlgelvwct-nh2
  Author: w. l. delano, m. h. ultsch, a. m. de vos, j. a. wells
  
  
• 1e0b.pdb. chromatin-binding 16-mar-00 1e0b
  Title: chromo shadow domain from fission yeast swi6 protein.
  Author: n. p. cowieson, j. f. partridge, r. c. allshire, p. j. mclaughlin
  Keywords: shadow, heterochromatin, swi6, pombe
  
• 1cm2.pdb. transferase 13-may-99 1cm2
  Title: structure of his15asp hpr after hydrolysis of ringed species.
  Author: s. napper, l. t. j. delbaere, e. b. waygood
  Keywords: succinimide, isoimide
  
• 3alc.pdb. dna binding protein 11-mar-99 3alc Zn (NMR, 17 structures)
  Title: ethanol regulon transcriptional activator dna-binding domain from aspergillus nidulans
  Author: r. cerdan, b. cahuzac, b. felenbok, e. guittet
  Keywords: dna-binding, transcriptional activator
  
• 1ex3.pdb. hydrolase 28-apr-00 1ex3
  Title: crystal structure of bovine chymotrypsinogen a (tetragonal)
  Author: p. e. pjura, a. m. lenhoff, s. a. leonard, a. g. gittis
  
  
• 1e0c.pdb. sulfurtransferase 23-mar-00 1e0c Mg
  Title: sulfurtransferase from azotobacter vinelandii
  Author: d. bordo, d. deriu, r. colnaghi, a. carpen, s. pagani, m. bolognesi
  Keywords: sulfur metabolism, thiosulfate:cyanide sulfurtransferase
  
• 1cm3.pdb. transferase 13-may-99 1cm3
  Title: his15asp hpr from e. coli
  Author: s. napper, e. b. waygood, l. t. j. delbaere
  
  
• 453d.pdb. deoxyribonucleic acid 18-feb-99 453d
  Title: 5'-d(*cp*gp*cp*gp*ap*ap*tp*tp*cp*gp*cp*g)-3'-benzimidazole complex
  Author: s. neidle
  
  
• 479d.pdb. dna/rna 08-jul-99 479d
  Title: crystal structure a dna:rna hybrid duplex, a dynamic model for rnase h recognition
  Author: y. xiong, m. sundaralingam
  Keywords: double helix
  
• 1exd.pdb. ligase/rna 02-may-00 1exd
  Title: crystal structure of a tight-binding glutamine trna bound to glutamine aminoacyl trna synthetase
  Author: t. l. bullock, l. d. sherlin, j. j. perona
  Keywords: trna-protein complex, trna aptamer
  
• 1ek5.pdb. isomerase 06-mar-00 1ek5
  Title: structure of human udp-galactose 4-epimerase in complex with nad+
  Author: j. b. thoden, t. m. wohlers, j. l. fridovich-keil, h. m. holden
  Keywords: epimerase, galactosemia
  
• 1cvu.pdb. oxidoreductase 24-aug-99 1cvu
  Title: crystal structure of arachidonic acid bound to the cyclooxygenase active site of cox-2
  Author: j. r. kiefer, j. l. pawlitz, k. t. moreland, r. a. stegeman, j. k. gierse, a. m. stevens, d. c. goodwin, s. w. rowlinson, l. j. marnett, w. c. stallings, r. g. kurumbail
  Keywords: cyclooxygenase, prostaglandin, arachidonate, endoperoxide
  
• 1qc5.pdb. cell adhesion 17-may-99 1qc5 Mg
  Title: i domain from integrin alpha1-beta1
  Author: c. c. deivanayagam, s. v. narayana
  Keywords: cell adhesion
  
• 1ek6.pdb. isomerase 06-mar-00 1ek6 Mg
  Title: structure of human udp-galactose 4-epimerase complexed with nadh and udp-glucose
  Author: j. b. thoden, t. m. wohlers, j. l. fridovich-keil, h. m. holden
  Keywords: short-chain dehydrogenase, galactosemia
  
• 1ef6.pdb. gene regulation 07-feb-00 1ef6 (theoretical model)
  Title: homology model of the human rev-erba ligand-binding domain
  Author: j. p. renaud
  
  
• 1qh6.pdb. hydrolase 11-may-99 1qh6 F
  Title: catalysis and specificity in enzymatic glycoside hydrolases: a 2,5b conformation for the glycosyl-enzyme intermidiate revealed by the structure of the bacillus agaradhaerens family 11 xylanase
  Author: e. sabini, g. sulzenbacher, m. dauter, z. dauter, p. l. jorgensen, m. schulein, c. dupont, g. j. davies, k. s. wilson
  
  
• 1ehw.pdb. transferase 23-feb-00 1ehw
  Title: human nucleoside diphosphate kinase 4
  Author: l. milon, p. meyer, m. chiadmi, a. munier, m. johansson, a. karlsson, i. lascu, j. capeau, j. janin, m-l. lacombe
  Keywords: nm23, mitochondrial, killer- of-prune
  
• 1qh7.pdb. hydrolase 11-may-99 1qh7
  Title: catalysis and specificity in enzymatic glycoside hydrolases: a 2,5b conformation for the glycosyl-enzyme intermidiate revealed by the structure of the bacillus agaradhaerens family 11 xylanase
  Author: e. sabini, g. sulzenbacher, m. dauter, z. dauter, p. l. jorgensen, m. schulein, c. dupont, g. j. davies, k. s. wilson
  
  
• 1qkg.pdb. deoxyribonucleic acid 20-jul-99 1qkg (NMR, minimized average structure)
  Title: dna decamer duplex containing t-t dewar photoproduct
  Author: j. -h. lee, s. -h. bae, y. -j. choi, b. -s. choi
  Keywords: dna photoproduct, dewar product, (6-4) adduct, mutagenesis, translesion replication
  
• 1mr8.pdb. metal transport 13-apr-99 1mr8 Ca
  Title: migration inhibitory factor-related protein 8 from human
  Author: k. ishikawa, a. nakagawa, i. tanaka, j. nishihira
  Keywords: crystal structure, mad, migration inhibitory factor_ related protein 8, s100 protein
  
• 1ddx.pdb. oxidoreductase 11-nov-99 1ddx
  Title: crystal structure of a mixture of arachidonic acid and prostaglandin bound to the cyclooxygenase active site of cox-2: prostaglandin structure
  Author: j. r. kiefer, j. l. pawlitz, k. t. moreland, r. a. stegeman, j. k. gierse, a. m. stevens, d. c. goodwin, s. w. rowlinson, l. j. marnett, w. c. stallings, r. g. kurumbail
  Keywords: cyclooxygenase, prostaglandin, arachidonate, endoperoxide, oxidoreductase
  
• 1dcx.pdb. oxidoreductase 05-nov-99 1dcx (theoretical model)
  Title: molecular model of arachidonic acid bound to the cyclooxygenase active site of cox-2
  Author: j. r. kiefer, j. l. pawlitz, k. t. moreland, r. a. stegeman, j. k. gierse, a. m. stevens, d. c. goodwin, s. w. rowlinson, l. j. marnett, w. c. stallings, r. g. kurumbail
  Keywords: cyclooxygenase, prostaglandin, arachidonate, endoperoxide, oxidoreductase
  
• 1emh.pdb. hydrolase/dna 16-mar-00 1emh
  Title: crystal structure of human uracil-dna glycosylase bound to uncleaved substrate-containing dna
  Author: s. s. parikh, g. slupphaug, h. e. krokan, g. m. blackburn, j. a. tainer
  Keywords: uracil-dna glycosylase, protein/dna
  
• 1ekx.pdb. transferase 09-mar-00 1ekx Ca
  Title: the isolated, unregulated catalytic trimer of aspartate transcarbamoylase complexed with bisubstrate analog pala (n- (phosphonacetyl)-l-aspartate)
  Author: j. a. endrizzi, p. t. beernink, t. alber, h. k. schachman
  Keywords: bisubstrate analog complex
  
• 1cm8.pdb. transferase 17-may-99 1cm8 Mg
  Title: phosphorylated map kinase p38-gamma
  Author: s. bellon, m. j. fitzgibbon, t. fox, h. m. hsiao, k. p. wilson
  Keywords: gamma, phosphorylation, map kinase
  
• 1c5h.pdb. hydrolase 24-nov-99 1c5h
  Title: hydrogen bonding and catalysis: an unexpected explanation for how a single amino acid substitution can change the ph optimum of a glycosidase
  Author: m. d. joshi, g. sidhu, i. pot, g. d. brayer, s. g. withers, l. p. mcintosh
  Keywords: ph-dependent enzyme mechanism, general acid/ base catalysis, nmr, x-ray cyrstallography, isotope shift, short hydrogen bonds, xylan
  
• 1dny.pdb. ligase 17-dec-99 1dny (NMR, 21 structures)
  Title: solution structure of pcp, a prototype for the peptidyl carrier domains of modular peptide synthetases
  Author: t. weber, r. baumgartner, c. renner, m. a. marahiel, t. a. holak
  Keywords: modular enzyme, domain, flexible region, 4'-phosphopantetheinyl cofactor, modular peptide synthetases, nonribosomal peptide synthesis, peptidyl carrier protein (pcp)
  
• 1exy.pdb. rna binding protein/rna 05-may-00 1exy (NMR, 12 structures)
  Title: solution structure of htlv-1 peptide bound to its rna aptamer target
  Author: f. jiang, a. gorin, w. hu, a. majumdar, s. baskerville, w. xu, a. ellington, d. j. patel
  Keywords: extended bound basic rex peptide, flap base, junctional base triplets, rna binding pocket architecture
  
• 1c5i.pdb. hydrolase 24-nov-99 1c5i F
  Title: hydrogen bonding and catalysis: an unexpected explanation for how a single amino acid substitution can change the ph optimum of a glycosidase
  Author: m. d. joshi, g. sidhu, i. pot, g. d. brayer, s. g. withers, l. p. mcintosh
  Keywords: ph-dependent enzyme mechanism, general acid/ base catalysis, nmr, x-ray crystallography, isotope shift, short hydrogen bonds, xylan
  
• 1emj.pdb. hydrolase/dna 16-mar-00 1emj
  Title: uracil-dna glycosylase bound to dna containing a 4'-thio- 2'deoxyuridine analog product
  Author: s. s. parikh, g. walcher, g. d. jones, g. slupphaug, h. e. krokan, g. m. blackburn, j. a. tainer
  Keywords: uracil-dna glycosylase, protein/dna
  
• 1efj.pdb. gene regulation 09-feb-00 1efj (theoretical model)
  Title: homology model of the mouse rvr ligand-binding domain
  Author: j. p. renaud
  
  
• 1dtl.pdb. structural protein 12-jan-00 1dtl Ca
  Title: crystal structure of calcium-saturated (3ca2+) cardiac troponin c complexed with the calcium sensitizer bepridil at 2.15 a resolution
  Author: y. li, m. l. love, j. a. putkey, c. cohen
  
  
• 1exl.pdb. deoxyribonucleic acid 03-may-00 1exl (NMR, 30 structures)
  Title: structure of an 11-mer dna duplex containing the carbocyclic nucleotide analog: 2'-deoxyaristeromycin
  Author: s. smirnov, f. johnson, r. marumoto, c. de los santos
  Keywords: modified nucleotides, 2'-deoxyaristeromycin
  
• 1ejn.pdb. hydrolase 22-apr-00 1ejn
  Title: urokinase plasminogen activator b-chain inhibitor complex
  Author: s. sperl, u. jacob, n. arroyo de prada, j. stuerzebecher, o. g. wilhelm, w. bode, v. magdolen, r. huber, l. moroder
  Keywords: upa, plasminogen activator, urokinase, inhibitor complex