BIOGRAPHICAL SKETCH

NAME Bernhard Rupp

POSITION TITLE Head, Macromolecular Crystallography and Structural Genomics

EDUCATION

INSTITUTION AND LOCATION	DEGREE (if applicable)	YEAR(s)	FIELD OF STUDY
University of Vienna, Vienna, Austria University of Vienna, Vienna, Austria, and ETH Zurich Postdoctoral Fellow, Austrian Sci. Foundation Lady Davis Fellow, Racah Inst. Physics, Jerusalem, Israel Postdoctoral Fellow, KFA Jülich, Germany Guest scientist, Laboratory for Neutron Scattering, PSI-ETH Zürich Postdoctoral Fellow, LLNL, Chemistry Dept. A.O.Univ. Professor of Molecular Structural Biology, University of Vienna, Austria	M.S. Ph.D. Dr. Habil.	1974-1982 1982-1984 1985 1986-1987 1987-1988 1988-1989 1989-1992 1998	Chemistry Physical Chemistry Structural Chemistry Structural Chemistry Complex Structures Synchrotron Studies Molecular and Structural Biology

EMPLOYMENT :

1981 - 1985 : Research and Teaching Associate, Austrian Science Foundation

1986 - 1987 : Lady Davis Postdoctoral Fellow, Racah Institute of Physics, Jerusalem, Israel

1987 - 1988 : Research Scientist at the Nuclear Research Center (KFA) Jülich, Germany

1988 - 1989 : Guest Scientist at the Neutron Scattering Laboratory (LNS) of the ETH Zürich, Switzerland

1989 - 1992 : University of California, Postdoctoral Fellow at LLNL, CMS Synchrotron Group

1993 - 2000 : University of California, Head of X-ray crystallography group, BBR Program, UC-LLNL

1997 - 2002 : LLNL Participating Research Team Leader, Advanced Light Source, LBNL

2000 – present : Head, Macromolecular Crystallography and Structural Genomics Group, UC-LLNL

PROFESSIONAL SOCIETIES AND HONORS :

Elected student participant of 1982 Nobel Laureate Conference, Lindau/Bodensee. Ph.D. and M.S. with distinction, Forchheimer Award 1986 (Israel). Nominated for the Walter Schottky Prize 1988 for structural and crystallographic work. Stipend for demonstrated excellence by the Academic Senate, University Vienna (three years, 1981-1983). Stipend for outstanding academic achievements by the Austrian Ministry for Science and Research (1981, 1982). Habilitation (venia docendi) to A.o.Univ. Professor of Molecular Structural Biology, University of Vienna, Austria (1988). Special Session Chair, American Crystallographic Association Annual Meeting 2001, Los Angeles; Program Committee, BIOS 2002; member of the NIH TB Structural Genomics Consortium. Sponsor, 2003 UCLA Seaborg Medal Symposium , Session Chair, ACA 2005 General meeting, W-1, Validation of Macromolecular Structures.

Elected member of the SSRL Users Organization Executive Committee (1998-2000) and UC BioStar and BioTech Review Panel, member of UCLA Chemistry and Biology Department Advisory Council. Wellcome Trust and DOE OBER/EPSCoR review panel, NIAID IRG member. Acta Crystallographica D, Phys. Rev. senior reviewer, JACS, JMB, JBC, JMMG, Structure, NAR, J.Bact. etc reviewer. US National Institutes of Health NIAID grant review IRG study section member. Nominated for US National Committee to the International Union of Crystallography (2004-2005), elected, American Crystallographic Association Standing Committee for Data Standards and Computing (2005-2008).

APPLICABLE RESEARCH EXPERIENCE, BIOSCIENCE

Head of macromolecular crystallography and structural genomics group, advanced biomolecular cryo-crystallography and synchrotron MAD and instrumentation techniques; crystal structures of antibody fragments, superantigens, apolipoptoteins, TB drug targets, neurotoxins. High throughput crystallization and crystallography, structural genomics, drug targets structures, machine learning, knowledge discovery. Founded and manages UC-LLNL HTP crystallography facility including molecular biology lab, crystallization robotics, spectroscopy, DLS, CD, and CCD area detectors. A.O.Univ. Professor of Molecular Structural Biology, University of Vienna, Austria. Web site for biomolecular crystallography and structural biology including crystallography tutorials at http://www-structure.llnl.gov.

RECENT JOURNAL PUBLICATIONS (>100 total)